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Product details

Anti-FoxO4 (phospho-S197) Antibody

Catalog number A01819S197

Price for A01819S197

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Size / count 100 µL

About this product

Boster Bio Anti-FoxO4 (phospho-S197) Antibody catalog # A01819S197. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A01819S197
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Forkhead box protein O4; Fork head domain transcription factor AFX1; FOXO4; AFX, AFX1, MLLT7
Gene Name
FOXO4
UniProt
P98177
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human FoxO4 around the phosphorylation site of Serine 197.
Clonality
Polyclonal
Tissue Specificity
Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
53684 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Forkhead box protein O4
Subcellular Location
Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
Protein Name
Forkhead box protein O4
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-FoxO4 (phospho-S197) Antibody?

The catalog number for Anti-FoxO4 (phospho-S197) Antibody is A01819S197.

What sizes are available for Anti-FoxO4 (phospho-S197) Antibody?

Anti-FoxO4 (phospho-S197) Antibody is available in the following size(s): 100 µL.

Is Anti-FoxO4 (phospho-S197) Antibody in stock?

Anti-FoxO4 (phospho-S197) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-FoxO4 (phospho-S197) Antibody?

The safety data sheet for Anti-FoxO4 (phospho-S197) Antibody is available here: https://www.bosterbio.com/msds?sku=A01819S197.

What is Anti-FoxO4 (phospho-S197) Antibody used for?

Boster Bio Anti-FoxO4 (phospho-S197) Antibody catalog # A01819S197. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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