Anti-Mouse Ring1 Antibody (C-term)

Catalog number A01824-80ul

Price for A01824-80ul

Size / count 80 µL

About this product

Boster Bio Anti-Mouse Ring1 Antibody (C-term) (Catalog # A01824) . Tested in WB application (s) . This antibody reacts with Mouse.

Specifications

Catalog number: A01824-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity (By similarity) .
Synonyms: E3 ubiquitin-protein ligase RING1, 632-, Polycomb complex protein RING1, RING finger protein 1, Transcription repressor Ring1A, Ring1, Ring1A, Rnf1
Gene Name: Ring1
UniProt: O35730
Host: Rabbit
Reactivity: Mouse
Immunogen: This Mouse Ring1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 306-340 amino acids from the C-terminal region of human Mouse Ring1.
Clonality: Polyclonal
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity (By similarity) .
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 42631 Da
Applications Notes: WB: 1:1000
Subcellular Location: Nucleus speckle.
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-Mouse Ring1 Antibody (C-term)?

The catalog number for Anti-Mouse Ring1 Antibody (C-term) is A01824-80ul.

What sizes are available for Anti-Mouse Ring1 Antibody (C-term)?

Anti-Mouse Ring1 Antibody (C-term) is available in the following size(s): 80 µL.

Is Anti-Mouse Ring1 Antibody (C-term) in stock?

Anti-Mouse Ring1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Mouse Ring1 Antibody (C-term)?

The safety data sheet for Anti-Mouse Ring1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A01824.

What is Anti-Mouse Ring1 Antibody (C-term) used for?

Boster Bio Anti-Mouse Ring1 Antibody (C-term) (Catalog # A01824) . Tested in WB application (s) . This antibody reacts with Mouse.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.