Anti-ETAR EDNRA Antibody

About this product

Boster Bio Anti-ETAR EDNRA Antibody catalog # A01828. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Monkey.

Specifications

Catalog number

A01828

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Endothelin-1 receptor; Endothelin A receptor; ET-A; ETA-R; hET-AR; EDNRA; ETA, ETRA

Gene Name

EDNRA

UniProt

P25101

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human EDNRA. AA range:378-427

Tissue Specificity

Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels. .

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

48722 MW

Gene Name Synonym

Endothelin-1 receptor

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.