Anti-NMDAR2B/GRIN2B Antibody

About this product

Boster Bio Anti-NMDAR2B/GRIN2B Antibody catalog # A01883-2. Tested in WB, IHC, ICC, IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A01883-2

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B) . The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.

Gene Name

GRIN2B

UniProt

Q13224

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human NMDAR2B/GRIN2B recombinant protein (Position: F1132-I1480) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Applications Notes

6

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.