Anti-PDH E1 Alpha/PDHA1 Antibody

About this product

Boster Bio Anti-PDH E1 Alpha/PDHA1 Antibody catalog # A01906-4. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A01906-4

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) . The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name

PDHA1

UniProt

P08559

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human PDH E1 Alpha/PDHA1 recombinant protein (Position: R45-S390) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.