Anti-ICOS ligand ICOSLG Antibody

About this product

Boster Bio Anti-ICOS ligand ICOSLG Antibody (Catalog # A01965) . Tested in ELISA, WB, IHC, IF applications. This antibody reacts with Human.

Specifications

Catalog number

A01965

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

GL50, Inducible T Cell Costimulator Ligand, B7-Related Protein, B7 Homolog, Inducible T-Cell Costimulator Ligand, B7-Like Protein Gl50, B7 Homologue, B7RP-1, ICOSL, B7-H2, B7RP1, B7H2, Transmembrane Protein B7-H2 ICOS Ligand, Inducible T-Cell Co-Stimulator Ligand, CD275 Antigen, ICOS Ligand, KIAA0653, ICOS-L, CD275, LICOS

Gene Name

ICOSLG

UniProt

O75144

Host

Rabbit

Reactivity

Human

Immunogen

ICOSLG antibody was raised against a peptide corresponding to 17 amino acids near the center of human ICOSLG. The immunogen is located within amino acids 150 - 200 of ICOSLG.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.

Applications

ELISA, WB, IHC, IF

Field of Research

Immunology

Purification

ICOSLG Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function (By similarity) . .

Storage Conditions

ICOSLG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

33349 MW

Gene Name Synonym

Inducible T cell costimulator ligand

Subcellular Location

Cell membrane

Prediction Reactivity

Mouse

Protein Name

Inducible T cell costimulator ligand

Isotype

IgG

Contents

ICOSLG Antibody is supplied in PBS containing 0.02% sodium azide.