Anti-Atlastin-1 ATL1 Antibody

About this product

Boster Bio Anti-Atlastin-1 ATL1 Antibody catalog # A01994. Tested in WB, IF applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A01994

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Atlastin-1;3.6.5.-; Brain-specific GTP-binding protein; GTP-binding protein 3; GBP-3; hGBP3; Guanine nucleotide-binding protein 3; Spastic paraplegia 3 protein A; ATL1; GBP3, SPG3A

Gene Name

ATL1

UniProt

Q8WXF7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant full length Human ATL1.

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level) .

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:27619977) . May also regulate Golgi biogenesis. May regulate axonal development.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

63544 MW

Gene Name Synonym

Atlastin-1

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Atlastin-1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2