Anti-BACH1 BRIP1 Antibody

About this product

Boster Bio Anti-BACH1 BRIP1 Antibody (Catalog # A01995) . Tested in ELISA, WB applications. This antibody reacts with Human.

Specifications

Catalog number

A01995

Size / count

100 µg

Dry ice

Yes

Hazardous

No

Discontinued

No

Background

BACH1 (also known as BRCA1 interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 and BRCA1-associated C-terminal helicase 1) is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1) . The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1) . The BACH1 gene may be a target of germline cancer-inducing mutations. BACH1 is localized within the nucleus and functions as a DNA-dependent ATPase and 5' to 3' DNA helicase. Two isoforms have been identified for this protein.

Synonyms

BACH1, BACH-1, BACH 1, Fanconi anemia group J protein, FACJ, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1, BRCA1 binding helicase like protein BACH1, BRCA1 interacting protein C terminal helicase 1, BRIP 1, ATP-dependent RNA helicase BRIP1, FANCJ, FANC-J, FANC J

Gene Name

BRIP1

UniProt

Q9BX63

Host

Rabbit

Reactivity

Human

Immunogen

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 92-104 of isoform 1 of human BACH1 protein.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling

Purification

This affinity purified antibody is directed against human BACH1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with BACH1 protein from human (100% homology) and chimpanzee (92% homology) . Expect reactivity with isoform 1 and isoform 2 of BACH1. Reactivity against BACH1 homologues from rat and mouse is not expected. Reactivity against homologues from other sources is not known.

Concentration

1.0 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Shipping Conditions

Dry Ice Shipping

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening. (Ship on dry ice.)

Isotype

IgG

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide