Anti-RuvB-like 1 RUVBL1 Antibody

About this product

Boster Bio Anti-RuvB-like 1 RUVBL1 Antibody (Catalog# A02049) . Tested in IHC, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number

A02049

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

RuvB-like 1;3.6.4.12;49 kDa TATA box-binding protein-interacting protein;49 kDa TBP-interacting protein;54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alpha; TAP54-alpha; RUVBL1; INO80H, NMP238, TIP49, TIP49A

Gene Name

RUVBL1

UniProt

Q9Y265

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant RuvB-like 1 protein (amino acids 1-268)

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed with high expression in heart, skeletal muscle and testis.

Applications

IHC, WB

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

50228 MW

Gene Name Synonym

RuvB-like 1

Subcellular Location

Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells.

Protein Name

RuvB-like 1

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.