Anti-CTIP RBBP8 Antibody

Catalog number A02076

Price for A02076

Size / count 100 µL

About this product

Boster Bio Anti-CTIP RBBP8 Antibody (Catalog# A02076) . Tested in IHC, ICC, IF, WB, ELISA applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number: A02076
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: RBBP8; CTIP; DNA endonuclease RBBP8; CtBP-interacting protein; CtIP; Retinoblastoma-binding protein 8; RBBP-8; Retinoblastoma-interacting protein and myosin-like; RIM; Sporulation in the absence of SPO11 protein 2 homolog; SAE2
Gene Name: RBBP8
UniProt: Q99708
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: A peptide derived from human CTIP. Immunogen sequence location: 293-342
Clonality: Polyclonal
Applications: IHC, ICC, IF, WB, ELISA
Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration: 0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Function: Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.
Storage Conditions: Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 101942 MW
Gene Name Synonym: DNA endonuclease RBBP8
Subcellular Location: Nucleus. Chromosome. Associates with sites of DNA damage in S/G2 phase (PubMed:10764811) . Ubiquitinated RBBP8 binds to chromatin following DNA damage (PubMed:16818604) .
Isotype: Rabbit IgG
Contents: PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-CTIP RBBP8 Antibody?

The catalog number for Anti-CTIP RBBP8 Antibody is A02076.

What sizes are available for Anti-CTIP RBBP8 Antibody?

Anti-CTIP RBBP8 Antibody is available in the following size(s): 100 µL.

Is Anti-CTIP RBBP8 Antibody in stock?

Anti-CTIP RBBP8 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CTIP RBBP8 Antibody?

The safety data sheet for Anti-CTIP RBBP8 Antibody is available here: https://www.bosterbio.com/msds?sku=A02076.

What is Anti-CTIP RBBP8 Antibody used for?

Boster Bio Anti-CTIP RBBP8 Antibody (Catalog# A02076) . Tested in IHC, ICC, IF, WB, ELISA applications. This antibody reacts with Human, Mouse.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.