Anti-NUP153 Antibody

About this product

Boster Bio Anti-NUP153 Antibody catalog # A02183. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number

A02183

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Nuclear pore complex protein Nup153;153 kDa nucleoporin; Nucleoporin Nup153; NUP153

Gene Name

NUP153

UniProt

P49790

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein

Clonality

Polyclonal

Applications

WB, ICC, IF, Flow Cytometry

Purification

ProA affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat- containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

153938 MW

Gene Name Synonym

Nuclear pore complex protein Nup153

Subcellular Location

Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Tightly associated with the nuclear membrane and lamina (By similarity) . Localized to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Dissociates from the NPC structure early during prophase of mitosis. Integrated in the newly assembled nuclear envelope of postmitotic cells early in G1. Colocalized with NUP98 and TPR to the nuclear basket at the nucleoplasmic side of the NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection. .

Protein Name

Nuclear pore complex protein Nup153

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2