Anti-eIF3L/Eif3S6Ip Antibody

About this product

Boster Bio Anti-eIF3L/Eif3S6Ip Antibody catalog # A02238. Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A02238

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Eukaryotic translation initiation factor 3 subunit L ; eIF3l ; Eukaryotic translation initiation factor 3 subunit 6-interacting protein ; Eukaryotic translation initiation factor 3 subunit E-interacting protein ; EIF3L ; EIF3EIP , EIF3S6IP ; HSPC021, HSPC025, MSTP005

Gene Name

EIF3L

UniProt

Q9Y262

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human IF3EI. AA range:1-50

Applications

WB, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

66727 MW

Gene Name Synonym

Eukaryotic translation initiation factor 3 subunit L

Subcellular Location

Cytoplasm .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.