Anti-DIO2 Antibody (Center) — image 1 of 4

Product details

Anti-DIO2 Antibody (Center)

Catalog number A02249-1-400ul

Price for A02249-1-400ul

Size / count 400 µL

About this product

Boster Bio Anti-DIO2 Antibody (Center) (Catalog # A02249-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number: A02249-1-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3) .
Synonyms: Type II iodothyronine deiodinase, 5DII, DIOII, Type 2 DI, Type-II 5'-deiodinase, DIO2, ITDI2, TXDI2
Gene Name: DIO2
UniProt: Q92813
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: This DIO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids of human DIO2.
Clonality: Polyclonal
Tissue Specificity: Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain (PubMed:8755651, PubMed:11165050) . Isoform 2 is expressed in the brain, heart, kidney and trachea (PubMed:11165050)
Applications: WB, Flow Cytometry, IHC-P
Field of Research: Cancer, Metabolism, Neuroscience, Signal Transduction
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) . Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 30552 Da
Subcellular Location: Membrane; Single-pass membrane protein
Prediction Reactivity: Pig
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-DIO2 Antibody (Center)?

The catalog number for Anti-DIO2 Antibody (Center) is A02249-1-400ul.

What sizes are available for Anti-DIO2 Antibody (Center)?

Anti-DIO2 Antibody (Center) is available in the following size(s): 400 µL.

Is Anti-DIO2 Antibody (Center) in stock?

Anti-DIO2 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DIO2 Antibody (Center)?

The safety data sheet for Anti-DIO2 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A02249-1.

What is Anti-DIO2 Antibody (Center) used for?

Boster Bio Anti-DIO2 Antibody (Center) (Catalog # A02249-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human, Mouse.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.