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Product details

Anti-Cytoplasmic protein NCK1 NCK1 Antibody

Catalog number A02260

Price for A02260

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Size / count 100 µL

About this product

Boster Bio Anti-Cytoplasmic protein NCK1 NCK1 Antibody catalog # A02260. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number
A02260
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Cytoplasmic protein NCK1; NCK adaptor protein 1; Nck-1; SH2/SH3 adaptor protein NCK-alpha; NCK1; NCK
Gene Name
NCK1
UniProt
P16333
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human NCK1 (NP_006144.1) .
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Adapter protein which associates with tyrosine- phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
42864 MW
Gene Name Synonym
Cytoplasmic protein NCK1
Subcellular Location
Cytoplasm. Endoplasmic reticulum. Nucleus. Mostly cytoplasmic, but shuttles between the cytoplasm and the nucleus. Import into the nucleus requires the interaction with SOCS7. Predominantly nuclear following genotoxic stresses, such as UV irradiation, hydroxyurea or mitomycin C treatments.
Protein Name
Cytoplasmic protein NCK1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Cytoplasmic protein NCK1 NCK1 Antibody?

The catalog number for Anti-Cytoplasmic protein NCK1 NCK1 Antibody is A02260.

What sizes are available for Anti-Cytoplasmic protein NCK1 NCK1 Antibody?

Anti-Cytoplasmic protein NCK1 NCK1 Antibody is available in the following size(s): 100 µL.

Is Anti-Cytoplasmic protein NCK1 NCK1 Antibody in stock?

Anti-Cytoplasmic protein NCK1 NCK1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Cytoplasmic protein NCK1 NCK1 Antibody?

The safety data sheet for Anti-Cytoplasmic protein NCK1 NCK1 Antibody is available here: https://www.bosterbio.com/msds?sku=A02260.

What is Anti-Cytoplasmic protein NCK1 NCK1 Antibody used for?

Boster Bio Anti-Cytoplasmic protein NCK1 NCK1 Antibody catalog # A02260. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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