Anti-MCM4 (P50) Antibody

About this product

Boster Bio Anti-MCM4 (P50) Antibody catalog # A02301. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A02301

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

DNA replication licensing factor MCM4;3.6.4.12; CDC21 homolog; P1-CDC21; MCM4; CDC21

Gene Name

MCM4

UniProt

P33991

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 30-80 of Human MCM4.

Clonality

Polyclonal

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

96558 MW

Gene Name Synonym

DNA replication licensing factor MCM4

Subcellular Location

Nucleus .

Protein Name

DNA replication licensing factor MCM4

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2