Anti-MAD2L2 Antibody (C-term) — image 1 of 3

Product details

Anti-MAD2L2 Antibody (C-term)

Catalog number A02357-3-400ul

Price for A02357-3-400ul

Size / count 400 µL

About this product

Boster Bio Anti-MAD2L2 Antibody (C-term) (Catalog # A02357-3) . Tested in IF, IHC-P, WB application (s) . This antibody reacts with Mouse.

Specifications

Catalog number: A02357-3-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
Synonyms: Mitotic spindle assembly checkpoint protein MAD2B, Mitotic arrest deficient 2-like protein 2, MAD2-like protein 2, REV7 homolog, hREV7, MAD2L2, MAD2B, REV7
Gene Name: MAD2L2
UniProt: Q9UI95
Host: Rabbit
Reactivity: Mouse
Immunogen: This MAD2L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-231 amino acids from the C-terminal region of human MAD2L2.
Clonality: Polyclonal
Tissue Specificity: Ubiquitously expressed.
Applications: IF, IHC-P, WB
Field of Research: Cancer, Cell Biology
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 114598251145982617719540172967301944365429656893201641942016419429656893296568932965689317296730114598251771954019443654
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 24334 Da
Subcellular Location: Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Chromosome. Note=Recruited to sites of chromosomal double-stranded breaks during G1 and S phase of the cell cycle
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-MAD2L2 Antibody (C-term)?

The catalog number for Anti-MAD2L2 Antibody (C-term) is A02357-3-400ul.

What sizes are available for Anti-MAD2L2 Antibody (C-term)?

Anti-MAD2L2 Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-MAD2L2 Antibody (C-term) in stock?

Anti-MAD2L2 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MAD2L2 Antibody (C-term)?

The safety data sheet for Anti-MAD2L2 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A02357-3.

What is Anti-MAD2L2 Antibody (C-term) used for?

Boster Bio Anti-MAD2L2 Antibody (C-term) (Catalog # A02357-3) . Tested in IF, IHC-P, WB application (s) . This antibody reacts with Mouse.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.