Anti-EYA1/4 Antibody

Catalog number A02376

Price for A02376

Size / count 100 µL

About this product

Boster Bio Anti-EYA1/4 Antibody catalog # A02376. Tested in WB applications. This antibody reacts with Human, Rat.

Specifications

Catalog number: A02376
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Eyes absent homolog 1;3.1.3.16
Gene Name: EYA1
UniProt: Q99502/O95677
Host: Rabbit
Reactivity: Human, Rat
Immunogen: A synthetic peptide corresponding to residues in Human EYA1/4
Clonality: Polyclonal
Tissue Specificity: In the embryo, highly expressed in kidney with lower levels in brain. Weakly expressed in lung. In the adult, highly expressed in heart and skeletal muscle. Weakly expressed in brain and liver. No expression in eye or kidney.
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity) . Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19234442) . Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis (By similarity) . Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity) . Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity) . Together with SIX1, it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 64593 MW
Applications Notes: WB: 1:500-1:1000
Gene Name Synonym: Eyes absent homolog 1
Subcellular Location: Cytoplasm
Protein Name: Eyes absent homolog 1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-EYA1/4 Antibody?

The catalog number for Anti-EYA1/4 Antibody is A02376.

What sizes are available for Anti-EYA1/4 Antibody?

Anti-EYA1/4 Antibody is available in the following size(s): 100 µL.

Is Anti-EYA1/4 Antibody in stock?

Anti-EYA1/4 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EYA1/4 Antibody?

The safety data sheet for Anti-EYA1/4 Antibody is available here: https://www.bosterbio.com/msds?sku=A02376.

What is Anti-EYA1/4 Antibody used for?

Boster Bio Anti-EYA1/4 Antibody catalog # A02376. Tested in WB applications. This antibody reacts with Human, Rat.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.