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Product details

Anti-SBDS Antibody

Catalog number A02396

Price for A02396

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Size / count 100 µL

About this product

Boster Bio Anti-SBDS Antibody catalog # A02396. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A02396
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Ribosome maturation protein SBDS; Shwachman-Bodian-Diamond syndrome protein; SBDS; CGI-97
Gene Name
SBDS
UniProt
Q9Y3A5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SBDS (NP_057122.2) .
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP- dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
28764 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Ribosome maturation protein SBDS
Subcellular Location
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus (PubMed:19602484 and PubMed:17475909) . Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (PubMed:19759903) .
Protein Name
Ribosome maturation protein SBDS
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-SBDS Antibody?

The catalog number for Anti-SBDS Antibody is A02396.

What sizes are available for Anti-SBDS Antibody?

Anti-SBDS Antibody is available in the following size(s): 100 µL.

Is Anti-SBDS Antibody in stock?

Anti-SBDS Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-SBDS Antibody?

The safety data sheet for Anti-SBDS Antibody is available here: https://www.bosterbio.com/msds?sku=A02396.

What is Anti-SBDS Antibody used for?

Boster Bio Anti-SBDS Antibody catalog # A02396. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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