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Product details

Anti-EKLF (W318) KLF1 Antibody

Catalog number A02450

Price for A02450

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Size / count 100 µL

About this product

Boster Bio Anti-EKLF (W318) KLF1 Antibody catalog # A02450. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A02450
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF; KLF1; EKLF
Gene Name
KLF1
UniProt
Q13351
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 288-335 of Human EKLF.
Clonality
Polyclonal
Tissue Specificity
Expression restricted to adult bone marrow and fetal liver. Not expressed in myeloid nor lymphoid cell lines.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
38221 MW
Gene Name Synonym
Krueppel-like factor 1
Subcellular Location
Nucleus
Protein Name
Krueppel-like factor 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-EKLF (W318) KLF1 Antibody?

The catalog number for Anti-EKLF (W318) KLF1 Antibody is A02450.

What sizes are available for Anti-EKLF (W318) KLF1 Antibody?

Anti-EKLF (W318) KLF1 Antibody is available in the following size(s): 100 µL.

Is Anti-EKLF (W318) KLF1 Antibody in stock?

Anti-EKLF (W318) KLF1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EKLF (W318) KLF1 Antibody?

The safety data sheet for Anti-EKLF (W318) KLF1 Antibody is available here: https://www.bosterbio.com/msds?sku=A02450.

What is Anti-EKLF (W318) KLF1 Antibody used for?

Boster Bio Anti-EKLF (W318) KLF1 Antibody catalog # A02450. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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