Anti-FIP1L1 Antibody

About this product

Boster Bio Anti-FIP1L1 Antibody catalog # A02452. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A02452

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Pre-mRNA 3'-end-processing factor FIP1; hFip1; FIP1-like 1 protein; Factor interacting with PAP; Rearranged in hypereosinophilia; FIP1L1; FIP1, RHE

Gene Name

FIP1L1

UniProt

Q6UN15

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human FIP1L1 (NP_001128409.1) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. FIP1L1 contributes to poly (A) site recognition and stimulates poly (A) addition. Binds to U-rich RNA sequence elements surrounding the poly (A) site. May act to tether poly (A) polymerase to the CPSF complex.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

66526 MW

Gene Name Synonym

Pre-mRNA 3'-end-processing factor FIP1

Subcellular Location

Nucleus.

Protein Name

Pre-mRNA 3'-end-processing factor FIP1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2