Anti-MCM6 Antibody

About this product

Boster Bio Anti-MCM6 Antibody catalog # A02755. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A02755

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

DNA replication licensing factor MCM6;3.6.4.12; p105MCM; MCM6

Gene Name

MCM6

UniProt

Q14566

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human MCM6.

Clonality

Polyclonal

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

92889 MW

Gene Name Synonym

DNA replication licensing factor MCM6

Subcellular Location

Nucleus. Binds to chromatin during G1 and detach from it during S phase.

Protein Name

DNA replication licensing factor MCM6

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2