Anti-5'-3' exoribonuclease 2 XRN2 Antibody

About this product

Boster Bio Anti-5'-3' exoribonuclease 2 XRN2 Antibody catalog # A02797. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Monkey.

Specifications

Catalog number

A02797

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

5'-3' exoribonuclease 2;3.1.13.-; DHM1-like protein; DHP protein; XRN2

Gene Name

XRN2

UniProt

Q9H0D6

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human XRN2. AA range:81-130

Tissue Specificity

Expressed in the spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Isoform 2 is expressed predominantly in peripheral blood leukocytes. .

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Possesses 5'->3' exoribonuclease activity (By similarity) . May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

108582 MW

Gene Name Synonym

5'-3' exoribonuclease 2

Subcellular Location

Nucleus, nucleolus .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.