Anti-REST corepressor 1 RCOR1 Antibody

Catalog number A02799

Price for A02799

Size / count 100 µL

About this product

Boster Bio Anti-REST corepressor 1 RCOR1 Antibody catalog # A02799. Tested in WB, ICC/IF, IP, ChIP applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number: A02799
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: REST corepressor 1; Protein CoREST; RCOR1; KIAA0071, RCOR
Gene Name: RCOR1
UniProt: Q9UKL0
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Recombinant fusion protein of human CoREST/CoREST/RCOR1 (NP_055971.2) .
Clonality: Polyclonal
Tissue Specificity: Ubiquitously expressed.
Applications: WB, ICC, IF, IP, ChIP
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 53327 MW
Gene Name Synonym: REST corepressor 1
Subcellular Location: Nucleus
Protein Name: REST corepressor 1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-REST corepressor 1 RCOR1 Antibody?

The catalog number for Anti-REST corepressor 1 RCOR1 Antibody is A02799.

What sizes are available for Anti-REST corepressor 1 RCOR1 Antibody?

Anti-REST corepressor 1 RCOR1 Antibody is available in the following size(s): 100 µL.

Is Anti-REST corepressor 1 RCOR1 Antibody in stock?

Anti-REST corepressor 1 RCOR1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-REST corepressor 1 RCOR1 Antibody?

The safety data sheet for Anti-REST corepressor 1 RCOR1 Antibody is available here: https://www.bosterbio.com/msds?sku=A02799.

What is Anti-REST corepressor 1 RCOR1 Antibody used for?

Boster Bio Anti-REST corepressor 1 RCOR1 Antibody catalog # A02799. Tested in WB, ICC/IF, IP, ChIP applications. This antibody reacts with Human, Mouse.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.