Anti-Spi-B Antibody

About this product

Boster Bio Anti-Spi-B Antibody (Catalog# A02805) . Tested in IHC, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number

A02805

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Transcription factor Spi-B; SPIB

Gene Name

SPIB

UniProt

Q01892

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant Spi-B protein (amino acids 50-260)

Clonality

Polyclonal

Tissue Specificity

Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver.

Applications

IHC, WB

Field of Research

Epigenetics and Nuclear Signaling, Pol II Transcription, Polymerase Associated Factors, Transcription, Transcription Factors

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN) -producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

28819 MW

Gene Name Synonym

Transcription factor Spi-B

Subcellular Location

Isoform 1: Nucleus.

Protein Name

Transcription factor Spi-B

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.