Product details

Anti-ERK5 MAPK7 Antibody

Catalog number A02812

Price for A02812

Size / count 100 µL

About this product

Boster Bio Anti-ERK5 MAPK7 Antibody catalog # A02812. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A02812
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Mitogen-activated protein kinase 7; MAP kinase 7; MAPK 7;2.7.11.24; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5; MAPK7; BMK1, ERK5, PRKM7
Gene Name: MAPK7
UniProt: Q13164
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human ERK5 (NP_002740.2) .
Clonality: Polyclonal
Tissue Specificity: Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.
Applications: WB, IHC, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras- independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 88386 MW
Gene Name Synonym: Mitogen-activated protein kinase 7
Subcellular Location: Cytoplasm. Nucleus. Nucleus, PML body. Translocates to the nucleus upon activation.
Protein Name: Mitogen-activated protein kinase 7
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-ERK5 MAPK7 Antibody?

The catalog number for Anti-ERK5 MAPK7 Antibody is A02812.

What sizes are available for Anti-ERK5 MAPK7 Antibody?

Anti-ERK5 MAPK7 Antibody is available in the following size(s): 100 µL.

Is Anti-ERK5 MAPK7 Antibody in stock?

Anti-ERK5 MAPK7 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ERK5 MAPK7 Antibody?

The safety data sheet for Anti-ERK5 MAPK7 Antibody is available here: https://www.bosterbio.com/msds?sku=A02812.

What is Anti-ERK5 MAPK7 Antibody used for?

Boster Bio Anti-ERK5 MAPK7 Antibody catalog # A02812. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.