Anti-PSMA/GCPII/FOLH1 Antibody

About this product

Boster Bio Anti-PSMA/GCPII/FOLH1 Antibody catalog # A02846-2. Tested in WB, IHC, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A02846-2

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.

Gene Name

FOLH1

UniProt

Q04609

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human FOLH1 recombinant protein (Position: 47-382) .

Clonality

Polyclonal

Applications

WB, IHC, ICC/IF, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.