Anti-ISL1 Antibody

Catalog number A02969

Price for A02969

Size / count 100 µL

About this product

Boster Bio Anti-ISL1 Antibody catalog # A02969. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A02969
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Insulin gene enhancer protein ISL-1; Islet-1; ISL1
Gene Name: ISL1
UniProt: P61371
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide of human Islet1 (NP_002193.2) .
Clonality: Polyclonal
Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Applications: WB
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart. Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart (By similarity) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 39036 MW
Applications Notes: WB: 1:500-1:2000
Gene Name Synonym: Insulin gene enhancer protein ISL-1
Subcellular Location: Nucleus
Protein Name: Insulin gene enhancer protein ISL-1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-ISL1 Antibody?

The catalog number for Anti-ISL1 Antibody is A02969.

What sizes are available for Anti-ISL1 Antibody?

Anti-ISL1 Antibody is available in the following size(s): 100 µL.

Is Anti-ISL1 Antibody in stock?

Anti-ISL1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ISL1 Antibody?

The safety data sheet for Anti-ISL1 Antibody is available here: https://www.bosterbio.com/msds?sku=A02969.

What is Anti-ISL1 Antibody used for?

Boster Bio Anti-ISL1 Antibody catalog # A02969. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.