Anti-UBE2S Antibody

Catalog number A03045

Price for A03045

Size / count 100 µL

About this product

Boster Bio Anti-UBE2S Antibody catalog # A03045. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A03045
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Ubiquitin-conjugating enzyme E2 S;2.3.2.23
Gene Name: UBE2S
UniProt: Q16763
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human UBE2S (NP_055316.2) .
Clonality: Polyclonal
Applications: WB, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338) . Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle- regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit (PubMed:19820702, PubMed:19822757, PubMed:27259151) . Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as an E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A (PubMed:16819549) . In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination (PubMed:20061386, PubMed:20622874) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 23845 MW
Gene Name Synonym: Ubiquitin-conjugating enzyme E2 S
Protein Name: Ubiquitin-conjugating enzyme E2 S
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-UBE2S Antibody?

The catalog number for Anti-UBE2S Antibody is A03045.

What sizes are available for Anti-UBE2S Antibody?

Anti-UBE2S Antibody is available in the following size(s): 100 µL.

Is Anti-UBE2S Antibody in stock?

Anti-UBE2S Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-UBE2S Antibody?

The safety data sheet for Anti-UBE2S Antibody is available here: https://www.bosterbio.com/msds?sku=A03045.

What is Anti-UBE2S Antibody used for?

Boster Bio Anti-UBE2S Antibody catalog # A03045. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.