Anti-PID MTA2 Antibody

Catalog number A03073

Price for A03073

Size / count 0.1 mg

About this product

Boster Bio Anti-PID MTA2 Antibody (Catalog # A03073) . Tested in ELISA, WB, ICC, IF, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A03073
Size / count: 0.1 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. The transcriptional activity of p53 is modulated by protein stability and acetylation. PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.
Synonyms: PID, MTA1L1, PID, Metastasis-associated protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 protein
Gene Name: MTA2
UniProt: O94776
Host: Rabbit
Reactivity: Human, Mouse, Rat
Cross Reactivity: PID antibody is predicted to not cross-react with MTA2
Immunogen: PID antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PID. The immunogen is located within the last 50 amino acids of PID.
Clonality: Polyclonal
Tissue Specificity: Widely expressed.
Applications: ELISA, WB, ICC, IF, IHC-P
Field of Research: Apoptosis
Purification: PID Antibody is affinity chromatography purified via peptide column.
Concentration: 1 mg/mL
Form: Liquid
Function: May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Storage Conditions: PID antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Observed Molecular Weight: 75023 MW
Gene Name Synonym: Metastasis associated 1 family, member 2
Subcellular Location: Nucleus
Protein Name: Metastasis associated 1 family, member 2
Isotype: IgG
Contents: PID Antibody is supplied in PBS containing 0.02% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PID MTA2 Antibody?

The catalog number for Anti-PID MTA2 Antibody is A03073.

What sizes are available for Anti-PID MTA2 Antibody?

Anti-PID MTA2 Antibody is available in the following size(s): 0.1 mg.

Is Anti-PID MTA2 Antibody in stock?

Anti-PID MTA2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PID MTA2 Antibody?

The safety data sheet for Anti-PID MTA2 Antibody is available here: https://www.bosterbio.com/msds?sku=A03073.

What is Anti-PID MTA2 Antibody used for?

Boster Bio Anti-PID MTA2 Antibody (Catalog # A03073) . Tested in ELISA, WB, ICC, IF, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.