Anti-Lysine-specific demethylase 5A KDM5A Antibody — image 1 of 2

Product details

Anti-Lysine-specific demethylase 5A KDM5A Antibody

Catalog number A03079

Price for A03079

Size / count 100 µL

About this product

Boster Bio Anti-Lysine-specific demethylase 5A KDM5A Antibody catalog # A03079. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number: A03079
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Lysine-specific demethylase 5A;1.14.11.-; Histone demethylase JARID1A; Jumonji/ARID domain-containing protein 1A; Retinoblastoma-binding protein 2; RBBP-2; KDM5A
Gene Name: KDM5A
UniProt: P29375
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant protein
Clonality: Polyclonal
Applications: WB, ICC, IF, Flow Cytometry
Purification: ProA affinity purified
Concentration: 1 mg/mL
Form: Liquid
Function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Regulates specific gene transcription through DNA-binding on 5'-CCGCCC-3' motif (PubMed:18270511) . May stimulate transcription mediated by nuclear receptors. Involved in transcriptional regulation of Hox proteins during cell differentiation (PubMed:19430464) . May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity) . Seems to act as a transcriptional corepressor for some genes such as MT1F and to favor the proliferation of cancer cells (PubMed:27427228) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 192095 MW
Gene Name Synonym: Lysine-specific demethylase 5A
Subcellular Location: Nucleus, nucleolus
Protein Name: Lysine-specific demethylase 5A
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Lysine-specific demethylase 5A KDM5A Antibody?

The catalog number for Anti-Lysine-specific demethylase 5A KDM5A Antibody is A03079.

What sizes are available for Anti-Lysine-specific demethylase 5A KDM5A Antibody?

Anti-Lysine-specific demethylase 5A KDM5A Antibody is available in the following size(s): 100 µL.

Is Anti-Lysine-specific demethylase 5A KDM5A Antibody in stock?

Anti-Lysine-specific demethylase 5A KDM5A Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Lysine-specific demethylase 5A KDM5A Antibody?

The safety data sheet for Anti-Lysine-specific demethylase 5A KDM5A Antibody is available here: https://www.bosterbio.com/msds?sku=A03079.

What is Anti-Lysine-specific demethylase 5A KDM5A Antibody used for?

Boster Bio Anti-Lysine-specific demethylase 5A KDM5A Antibody catalog # A03079. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.