Anti-PREX1 Antibody (C-term)

Catalog number A03098-1-400ul

Price for A03098-1-400ul

Size / count 400 µL

About this product

Boster Bio Anti-PREX1 Antibody (C-term) (Catalog # A03098-1) . Tested in IHC-P, WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: A03098-1-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs) . It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Synonyms: Phosphatidylinositol 3,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns (3,5) -dependent Rac exchanger 1, PREX1, KIAA1415
Gene Name: PREX1
UniProt: Q8TCU6
Host: Rabbit
Reactivity: Human
Immunogen: This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1.
Clonality: Polyclonal
Tissue Specificity: Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues
Applications: IHC-P, WB, Flow Cytometry
Field of Research: Cell Biology, Signal Transduction, Chemokine signaling, Inflammation
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 186203 Da
Subcellular Location: Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PREX1 Antibody (C-term)?

The catalog number for Anti-PREX1 Antibody (C-term) is A03098-1-400ul.

What sizes are available for Anti-PREX1 Antibody (C-term)?

Anti-PREX1 Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-PREX1 Antibody (C-term) in stock?

Anti-PREX1 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PREX1 Antibody (C-term)?

The safety data sheet for Anti-PREX1 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A03098-1.

What is Anti-PREX1 Antibody (C-term) used for?

Boster Bio Anti-PREX1 Antibody (C-term) (Catalog # A03098-1) . Tested in IHC-P, WB, Flow Cytometry application (s) . This antibody reacts with Human.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.