Product details

Anti-UBR5 Antibody

Catalog number A03160

Price for A03160

Size / count 100 µL

About this product

Boster Bio Anti-UBR5 Antibody catalog # A03160. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number: A03160
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: E3 ubiquitin-protein ligase UBR5;2.3.2.26; E3 ubiquitin-protein ligase, HECT domain-containing 1; HECT-type E3 ubiquitin transferase UBR5; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein; UBR5; EDD, EDD1, HYD, KIAA0896
Gene Name: UBR5
UniProt: O95071
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human EDD. AA range:1-50
Clonality: Polyclonal
Tissue Specificity: Widely expressed. Most abundant in testis and expressed at high levels in brain, pituitary and kidney.
Applications: WB, IHC, IF, ELISA
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Form: Liquid
Function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity) . Involved in maturation and/or transcriptional regulation of mRNA by activating CDK9 by polyubiquitination. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development. Ubiquitinates acetylated PCK1. Also acts as a regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'- linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 309352 MW
Gene Name Synonym: E3 ubiquitin-protein ligase UBR5
Subcellular Location: Nucleus.
Protein Name: E3 ubiquitin-protein ligase UBR5
Isotype: IgG
Contents: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-UBR5 Antibody?

The catalog number for Anti-UBR5 Antibody is A03160.

What sizes are available for Anti-UBR5 Antibody?

Anti-UBR5 Antibody is available in the following size(s): 100 µL.

Is Anti-UBR5 Antibody in stock?

Anti-UBR5 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-UBR5 Antibody?

The safety data sheet for Anti-UBR5 Antibody is available here: https://www.bosterbio.com/msds?sku=A03160.

What is Anti-UBR5 Antibody used for?

Boster Bio Anti-UBR5 Antibody catalog # A03160. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.