Anti-BPIFA1 Antibody

About this product

Boster Bio Anti-BPIFA1 Antibody catalog # A03162. Tested in WB applications. This antibody reacts with Human, Rat.

Specifications

Catalog number

A03162

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

BPI fold-containing family A member 1; Lung-specific protein X; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; Secretory protein in upper respiratory tracts; Short PLUNC1; SPLUNC1; Tracheal epithelium-enriched protein; Von Ebner protein Hl; BPIFA1; LUNX, NASG, PLUNC, SPLUNC1, SPURT; UNQ787/PRO1606

Gene Name

BPIFA1

UniProt

Q9NP55

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthetic peptide corresponding to residues in Human BPIFA1

Clonality

Polyclonal

Tissue Specificity

Lung, upper airways and nasopharyngeal regions, including trachea and nasal epithelium. Specifically expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. Highest expression in the trachea and progressive decrease from proximal (bronchial) to distal (bronchiolar) airways. Also expressed in lung cancers and some other types of cancer.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS) . Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

26713 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

BPI fold-containing family A member 1

Subcellular Location

Secreted

Protein Name

BPI fold-containing family A member 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2