Anti-ROR1 Antibody

About this product

Boster Bio Anti-ROR1 Antibody (Catalog # A03192) . Tested in IHC-P, WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number

A03192-50ul

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

ROR1 is a receptor protein tyrosine kinase whose cellular role has not been determined. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Studies of a similar protein in mouse suggest that this protein may interact with another receptor protein tyrosine kinase and may be involved in skeletal and cardiac development.

Synonyms

Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1, ROR1, NTRKR1

Gene Name

ROR1

UniProt

Q01973

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ROR1 antibody is generated from rabbits immunized with recombinant human ROR1 protein (aa region: 112 - 399) .

Clonality

Polyclonal

Tissue Specificity

Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm

Applications

IHC-P, WB, Flow Cytometry

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

104283 Da

Subcellular Location

Membrane; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9Z139}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.