Anti-MYL2 Monoclonal Antibody

About this product

Boster Bio Anti-MYL2 Monoclonal Antibody catalog # A03215. Tested in WB, ELISA applications. This antibody reacts with Human.

Specifications

Catalog number

A03215

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform ; MLC-2 ; MLC-2v; Cardiac myosin light chain 2 ; Myosin light chain 2, slow skeletal/ventricular muscle isoform ; MLC-2s/v ; Ventricular myosin light chain 2 ; MYL2 ; MLC2

Gene Name

MYL2

UniProt

P10916

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of MYL2 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 7C9

Applications

WB, ELISA

Purification

Ascitic fluid

Concentration

1 mg/mL

Form

Liquid

Function

Contractile protein that plays a role in heart development and function (By similarity) . Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) . During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

18789 MW

Gene Name Synonym

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

Subcellular Location

Cytoplasm, myofibril, sarcomere, A band .

Contents

Ascitic fluid containing 0.03% sodium azide.