Anti-PEG10 Monoclonal Antibody

About this product

Boster Bio Anti-PEG10 Monoclonal Antibody catalog # A03240. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Specifications

Catalog number

A03240

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Retrotransposon-derived protein PEG10; Embryonal carcinoma differentiation-regulated protein; Mammalian retrotransposon-derived protein 2; Myelin expression factor 3-like protein 1; MEF3-like protein 1; Paternally expressed gene 10 protein; Retrotransposon gag domain-containing protein 3; Retrotransposon-derived gag-like polyprotein; Ty3/Gypsy-like protein; PEG10; EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3

Gene Name

PEG10

UniProt

Q86TG7

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of PEG10 (aa1-120) expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 1B1C4

Tissue Specificity

Expressed in the cytotrophoblast layer but not in the overlying syncytiotrophoblast of the placenta. Expressed in prostate and breast carcinomas but not in normal breast and prostate epithelial cells. Expressed in the Hep-G2 cell line (at protein level) . Expressed in brain, liver, spleen, kidney, thymus, lung, ovary, testis, reactive lymph node, skeletal muscle, adipose tissue and placenta. Expressed in pancreatic and hepatocellular carcinomas (HCC) . .

Applications

WB, IHC, IF, ELISA

Purification

Ascitic fluid

Sensitivity

>5000 cells

Concentration

1 mg/mL

Form

Liquid

Function

Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity) . May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

80173 MW

Gene Name Synonym

Retrotransposon-derived protein PEG10

Subcellular Location

Nucleus. Cytoplasm. Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the Hep-G2 cell line. Colocalized with ALK1.

Contents

Ascitic fluid containing 0.03% sodium azide.