Anti-Proteasome subunit beta type-5 PSMB5 Antibody

About this product

Boster Bio Anti-Proteasome subunit beta type-5 PSMB5 Antibody catalog # A03418. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A03418

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Proteasome subunit beta type-5;3.4.25.1

Gene Name

PSMB5

UniProt

P28074

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PSMB5 (NP_002788.1) .

Clonality

Polyclonal

Applications

WB, ICC, IF, IP

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) . Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

28480 MW

Gene Name Synonym

Proteasome subunit beta type-5

Subcellular Location

Cytoplasm

Protein Name

Proteasome subunit beta type-5

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2