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Product details

Anti-Actin-related protein 3 ACTR3 Antibody

Catalog number A03423

Price for A03423

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Size / count 100 µL

About this product

Boster Bio Anti-Actin-related protein 3 ACTR3 Antibody catalog # A03423. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number
A03423
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Actin-related protein 3; Actin-like protein 3; ACTR3; ARP3
Gene Name
ACTR3
UniProt
P61158
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ACTR3.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076) . Seems to contact the pointed end of the daughter actin filament (PubMed:9000076) . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947) . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double- strand breaks (DSBs) (PubMed:29925947) . Plays a role in ciliogenesis (PubMed:20393563) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
47371 MW
Gene Name Synonym
Actin-related protein 3
Subcellular Location
Cytoplasm, cytoskeleton
Protein Name
Actin-related protein 3
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Actin-related protein 3 ACTR3 Antibody?

The catalog number for Anti-Actin-related protein 3 ACTR3 Antibody is A03423.

What sizes are available for Anti-Actin-related protein 3 ACTR3 Antibody?

Anti-Actin-related protein 3 ACTR3 Antibody is available in the following size(s): 100 µL.

Is Anti-Actin-related protein 3 ACTR3 Antibody in stock?

Anti-Actin-related protein 3 ACTR3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Actin-related protein 3 ACTR3 Antibody?

The safety data sheet for Anti-Actin-related protein 3 ACTR3 Antibody is available here: https://www.bosterbio.com/msds?sku=A03423.

What is Anti-Actin-related protein 3 ACTR3 Antibody used for?

Boster Bio Anti-Actin-related protein 3 ACTR3 Antibody catalog # A03423. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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