Anti-DOCK 180 (K1692) Antibody

Catalog number A03440

Price for A03440

Size / count 100 µL

About this product

Boster Bio Anti-DOCK 180 (K1692) Antibody catalog # A03440. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Specifications

Catalog number: A03440
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Dedicator of cytokinesis protein 1;180 kDa protein downstream of CRK; DOCK180; DOCK1
Gene Name: DOCK1
UniProt: Q14185
Host: Rabbit
Reactivity: Human, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 1660-1719 of Human DOCK 180.
Clonality: Polyclonal
Tissue Specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
Applications: WB, IHC
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829) . Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 215346 MW
Gene Name Synonym: Dedicator of cytokinesis protein 1
Subcellular Location: Cytoplasm . Membrane . Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate. .
Protein Name: Dedicator of cytokinesis protein 1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-DOCK 180 (K1692) Antibody?

The catalog number for Anti-DOCK 180 (K1692) Antibody is A03440.

What sizes are available for Anti-DOCK 180 (K1692) Antibody?

Anti-DOCK 180 (K1692) Antibody is available in the following size(s): 100 µL.

Is Anti-DOCK 180 (K1692) Antibody in stock?

Anti-DOCK 180 (K1692) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DOCK 180 (K1692) Antibody?

The safety data sheet for Anti-DOCK 180 (K1692) Antibody is available here: https://www.bosterbio.com/msds?sku=A03440.

What is Anti-DOCK 180 (K1692) Antibody used for?

Boster Bio Anti-DOCK 180 (K1692) Antibody catalog # A03440. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.