Anti-WNT16 Antibody (C-term)

About this product

Boster Bio Anti-WNT16 Antibody (C-term) (Catalog # A03606-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number

A03606-1-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.

Synonyms

Protein Wnt-16, WNT16

Gene Name

WNT16

UniProt

Q9UBV4

Host

Rabbit

Reactivity

Human

Immunogen

This WNT16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the C-terminal region of human WNT16.

Clonality

Polyclonal

Tissue Specificity

Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas

Applications

WB, IHC-P

Field of Research

Signal Transduction, Anti-Wnt-Pathway (plus Lgr5) Antibodies

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

40690 Da

Subcellular Location

Secreted, extracellular space, extracellular matrix

Prediction Reactivity

Mouse

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.