Anti-IL-37 Antibody

Catalog number A03607

Price for A03607

Size / count 100 µg

About this product

Boster Bio Anti-IL-37 Antibody (Catalog# A03607) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A03607
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Interleukin-37; FIL1 zeta; IL-1X; Interleukin-1 family member 7; IL-1F7; Interleukin-1 homolog 4; IL-1H; IL-1H4; Interleukin-1 zeta; IL-1 zeta; Interleukin-1-related protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z, IL1F7, IL1H4, IL1RP1
Gene Name: IL37
UniProt: Q9NZH6
Host: Rabbit
Reactivity: Human
Immunogen: Full length recombinant IL-37 protein
Clonality: Polyclonal
Tissue Specificity: In general, low constitutive expression, if any, in healthy tissues; high expression in inflammatory counterparts, including in synovial tissues from individuals with active rheumatoid arthritis. Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node. Isoform D and isoform E were found only in testis and bone marrow. Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart.
Applications: WB
Field of Research: Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage/Inflammation
Purification: Protein A Chromatography
Concentration: 0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Function: Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation. .
Storage Conditions: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Observed Molecular Weight: 24126 MW
Applications Notes: Western blot: 2-4 μg/ml
Gene Name Synonym: Interleukin-37
Subcellular Location: Cytoplasm, cytosol. Nucleus. Secreted. Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation.
Protein Name: Interleukin-37
Isotype: Rabbit IgG
Contents: 100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-IL-37 Antibody?

The catalog number for Anti-IL-37 Antibody is A03607.

What sizes are available for Anti-IL-37 Antibody?

Anti-IL-37 Antibody is available in the following size(s): 100 µg.

Is Anti-IL-37 Antibody in stock?

Anti-IL-37 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-IL-37 Antibody?

The safety data sheet for Anti-IL-37 Antibody is available here: https://www.bosterbio.com/msds?sku=A03607.

What is Anti-IL-37 Antibody used for?

Boster Bio Anti-IL-37 Antibody (Catalog# A03607) . Tested in WB application (s) . This antibody reacts with Human.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.