Product details

Anti-UPF2 Antibody

Catalog number A03627

Price for A03627

Size / count 100 µL

About this product

Boster Bio Anti-UPF2 Antibody catalog # A03627. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Specifications

Catalog number: A03627
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Regulator of nonsense transcripts 2; Nonsense mRNA reducing factor 2; Up-frameshift suppressor 2 homolog; hUpf2; UPF2; KIAA1408, RENT2
Gene Name: UPF2
UniProt: Q9HAU5
Host: Rabbit
Reactivity: Human, Rat
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1272 of human UPF2 (NP_542166.1) .
Clonality: Polyclonal
Tissue Specificity: Ubiquitous.
Applications: WB, IHC
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) . Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 147810 MW
Gene Name Synonym: Regulator of nonsense transcripts 2
Subcellular Location: Cytoplasm, perinuclear region
Protein Name: Regulator of nonsense transcripts 2
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-UPF2 Antibody?

The catalog number for Anti-UPF2 Antibody is A03627.

What sizes are available for Anti-UPF2 Antibody?

Anti-UPF2 Antibody is available in the following size(s): 100 µL.

Is Anti-UPF2 Antibody in stock?

Anti-UPF2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-UPF2 Antibody?

The safety data sheet for Anti-UPF2 Antibody is available here: https://www.bosterbio.com/msds?sku=A03627.

What is Anti-UPF2 Antibody used for?

Boster Bio Anti-UPF2 Antibody catalog # A03627. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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