Anti-Stabilin-2 STAB2 Antibody

About this product

Boster Bio Anti-Stabilin-2 STAB2 Antibody catalog # A03742. Tested in ELISA, IHC, ICC, IF applications. This antibody reacts with Mouse.

Specifications

Catalog number

A03742

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Stabilin-2; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2; Hyaluronan receptor for endocytosis;190 kDa form stabilin-2;190 kDa hyaluronan receptor for endocytosis; STAB2

Gene Name

STAB2

UniProt

Q8WWQ8

Host

Rabbit

Reactivity

Mouse

Clonality

Polyclonal

Tissue Specificity

Highly expressed in sinusoidal endothelial cells of liver, spleen and lymph nodes. Also expressed in non SEC- cells such as HMDMs (monocyte-derivedmacrophages), HAMs (T-cell leukemia virus type 1-associated myelopathy), and several macrophage cell line.

Applications

ELISA, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA) . Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE) . May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

276988 MW

Gene Name Synonym

Stabilin-2

Subcellular Location

Cell membrane

Protein Name

Stabilin-2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2