Anti-Hippocalcin Antibody (N-term)

About this product

Boster Bio Anti-Hippocalcin Antibody (N-term) (Catalog # A03907) . Tested in WB, IHC-P application (s) . This antibody reacts with Human, Mouse.

Specifications

Catalog number

A03907-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Hippocalcin is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species.

Synonyms

Neuron-specific calcium-binding protein hippocalcin, Calcium-binding protein BDR-2, HPCA, BDR2

Gene Name

HPCA

UniProt

P84074

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Hippocalcin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human Hippocalcin.

Clonality

Polyclonal

Tissue Specificity

Brain specific.

Applications

WB, IHC-P

Field of Research

Neuroscience

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

28398555

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

22427 Da

Subcellular Location

Cytoplasm, cytosol {ECO:0000250|UniProtKB:P84076, ECO:0000269|PubMed:28398555}. Membrane {ECO:0000250|UniProtKB:P84076}; Peripheral membrane protein {ECO:0000250|UniProtKB:P84076} Note=Association with membranes is calcium-dependent (By similarity) Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (PubMed:28398555) {ECO:0000250|UniProtKB:P84076, ECO:0000269|PubMed:28398555}

Prediction Reactivity

Bovine, Pig, Rat

Isotype

Rabbit IgG

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.