Anti-FBXO7 Antibody

About this product

Boster Bio Anti-FBXO7 Antibody catalog # A04086. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A04086

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

F-box only protein 7; FBXO7; FBX7

Gene Name

FBXO7

UniProt

Q9Y3I1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from human protein at AA range: 371-420

Applications

WB, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

58503 MW

Gene Name Synonym

F-box only protein 7

Subcellular Location

Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria.

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.