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Product details

Anti-OASL Antibody (C-term)

Catalog number A04123-1-80ul

Price for A04123-1-80ul

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Size / count 80 µL

About this product

Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number
A04123-1-80ul
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
Synonyms
2'-5'-oligoadenylate synthase-like protein, 2'-5'-OAS-related protein, 2'-5'-OAS-RP, 59 kDa 2'-5'-oligoadenylate synthase-like protein, Thyroid receptor-interacting protein 14, TR-interacting protein 14, TRIP-14, p59 OASL, p59OASL, OASL, TRIP14
Gene Name
OASL
UniProt
Q15646
Host
Rabbit
Reactivity
Human
Immunogen
This OASL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human OASL.
Clonality
Polyclonal
Tissue Specificity
Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis
Applications
WB, IHC-P
Field of Research
Cell Biology, Immunology, Antiviral Signaling, Innate Immunity
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
59226 Da
Subcellular Location
[Isoform p56]: Nucleus, nucleolus. Cytoplasm.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-OASL Antibody (C-term)?

The catalog number for Anti-OASL Antibody (C-term) is A04123-1-80ul.

What sizes are available for Anti-OASL Antibody (C-term)?

Anti-OASL Antibody (C-term) is available in the following size(s): 80 µL.

Is Anti-OASL Antibody (C-term) in stock?

Anti-OASL Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-OASL Antibody (C-term)?

The safety data sheet for Anti-OASL Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A04123-1.

What is Anti-OASL Antibody (C-term) used for?

Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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