Anti-OASL Antibody (C-term)

Catalog number A04123-1-400ul

Price for A04123-1-400ul

Size / count 400 µL

About this product

Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A04123-1-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
Synonyms: 2'-5'-oligoadenylate synthase-like protein, 2'-5'-OAS-related protein, 2'-5'-OAS-RP, 59 kDa 2'-5'-oligoadenylate synthase-like protein, Thyroid receptor-interacting protein 14, TR-interacting protein 14, TRIP-14, p59 OASL, p59OASL, OASL, TRIP14
Gene Name: OASL
UniProt: Q15646
Host: Rabbit
Reactivity: Human
Immunogen: This OASL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human OASL.
Clonality: Polyclonal
Tissue Specificity: Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis
Applications: WB, IHC-P
Field of Research: Cell Biology, Immunology, Antiviral Signaling, Innate Immunity
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 59226 Da
Subcellular Location: [Isoform p56]: Nucleus, nucleolus. Cytoplasm.
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-OASL Antibody (C-term)?

The catalog number for Anti-OASL Antibody (C-term) is A04123-1-400ul.

What sizes are available for Anti-OASL Antibody (C-term)?

Anti-OASL Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-OASL Antibody (C-term) in stock?

Anti-OASL Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-OASL Antibody (C-term)?

The safety data sheet for Anti-OASL Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A04123-1.

What is Anti-OASL Antibody (C-term) used for?

Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.