Anti-ANO6 Antibody (N-term)

Catalog number A04251-400ul

Price for A04251-400ul

Size / count 400 µL

About this product

Boster Bio Anti-ANO6 Antibody (N-term) (Catalog # A04251) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A04251-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: May act as a calcium-activated chloride channel.
Synonyms: Anoctamin-6, Small-conductance calcium-activated nonselective cation channel, SCAN channel, Transmembrane protein 16F, ANO6, TMEM16F
Gene Name: ANO6
UniProt: Q4KMQ2
Host: Rabbit
Reactivity: Human
Immunogen: This ANO6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human ANO6.
Clonality: Polyclonal
Tissue Specificity: Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer
Applications: WB
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium- dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity) . Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 106165 Da
Applications Notes: WB: 1:1000
Subcellular Location: Cell membrane; Multi-pass membrane protein. Note=Shows an intracellular localization according to PubMed:22075693
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-ANO6 Antibody (N-term)?

The catalog number for Anti-ANO6 Antibody (N-term) is A04251-400ul.

What sizes are available for Anti-ANO6 Antibody (N-term)?

Anti-ANO6 Antibody (N-term) is available in the following size(s): 400 µL.

Is Anti-ANO6 Antibody (N-term) in stock?

Anti-ANO6 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ANO6 Antibody (N-term)?

The safety data sheet for Anti-ANO6 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A04251.

What is Anti-ANO6 Antibody (N-term) used for?

Boster Bio Anti-ANO6 Antibody (N-term) (Catalog # A04251) . Tested in WB application (s) . This antibody reacts with Human.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.