Anti-EIF3B Antibody

Catalog number A04318

Price for A04318

Size / count 100 µL

About this product

Boster Bio Anti-EIF3B Antibody catalog # A04318. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A04318
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Eukaryotic translation initiation factor 3 subunit B
Gene Name: EIF3B
UniProt: P55884
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human eIF3B (NP_003742.2) .
Clonality: Polyclonal
Applications: WB, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815) . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632) . The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 92482 MW
Gene Name Synonym: Eukaryotic translation initiation factor 3 subunit B
Subcellular Location: Cytoplasm
Protein Name: Eukaryotic translation initiation factor 3 subunit B
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-EIF3B Antibody?

The catalog number for Anti-EIF3B Antibody is A04318.

What sizes are available for Anti-EIF3B Antibody?

Anti-EIF3B Antibody is available in the following size(s): 100 µL.

Is Anti-EIF3B Antibody in stock?

Anti-EIF3B Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EIF3B Antibody?

The safety data sheet for Anti-EIF3B Antibody is available here: https://www.bosterbio.com/msds?sku=A04318.

What is Anti-EIF3B Antibody used for?

Boster Bio Anti-EIF3B Antibody catalog # A04318. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.