Anti-TYSY Antibody (C-term) — image 1 of 6

Product details

Anti-TYSY Antibody (C-term)

Catalog number A04320-3-400ul

Price for A04320-3-400ul

Size / count 400 µL

About this product

Boster Bio Anti-TYSY Antibody (C-term) (Catalog # A04320-3) . Tested in Flow Cytometry, IF, IHC-P, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A04320-3-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.
Synonyms: Thymidylate synthase, TS, TSase, TYMS, TS
Gene Name: TYMS
UniProt: P04818
Host: Rabbit
Reactivity: Human
Immunogen: This TYSY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human TYSY.
Clonality: Polyclonal
Applications: Flow Cytometry, IF, IHC-P, WB
Field of Research: Metabolism, Mitochondria
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Catalyzes the reductive methylation of 2'-deoxyuridine 5'- monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1- carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 35716 Da
Subcellular Location: Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-TYSY Antibody (C-term)?

The catalog number for Anti-TYSY Antibody (C-term) is A04320-3-400ul.

What sizes are available for Anti-TYSY Antibody (C-term)?

Anti-TYSY Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-TYSY Antibody (C-term) in stock?

Anti-TYSY Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TYSY Antibody (C-term)?

The safety data sheet for Anti-TYSY Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A04320-3.

What is Anti-TYSY Antibody (C-term) used for?

Boster Bio Anti-TYSY Antibody (C-term) (Catalog # A04320-3) . Tested in Flow Cytometry, IF, IHC-P, WB application (s) . This antibody reacts with Human.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.